The combined intake of CBD and antidepressants can cause certain interactions that can change the way both substances are metabolized in the liver. Despite the lack of strong evidence that CBD interacts directly with antidepressants, there is a well-founded belief that taking them at the same time presents some problems. CBD does not have the same binding capacities as THC, which limits its affinity for CB1 and CB2 receptors. People concerned about consuming too much THC may consider consuming CBD oil or another faster-acting product, such as a tincture, vaporizer, or dried flower, to consume just in case.
As for actual clinical practice, I haven't heard any stories of people who have suffered clinical decompensation from adding CBD to their regimen, he says. They act similar to CBD in the way they block the reabsorption of serotonin in the brain, resulting in higher concentrations in the bloodstream and improving mood. There is some scientific evidence that CBD can alleviate the symptoms of depression, although these results have not yet been replicated in large scale clinical trials. Cannabidiol (CBD) is its own complex cannabinoid, which shows wide potential for many users, both for medicinal and recreational purposes.
Simply put, taking CBD at the same time as substances that cause drowsiness, such as benzodiazepines, antipsychotics, antidepressants, or alcohol, can lead to increased fatigue, sleepiness, and possibly accidental driving accidents. In short, Grinspoon states that possible interactions should be considered more “hypothetical than real”, and that the side effect profile of CBD is “very minimal”. Studies have shown that CBD can stimulate the formation of new neurons in the brain, improving the plasticity of the hippocampus. One of the main reasons why people choose CBD instead of these treatments is that it doesn't cause the user to become dependent on it.
Although it's touted as a natural, holistic, and safe way to control a variety of health issues, you might be wondering if you can take CBD and antidepressants together. There's no denying that CBD, also known as cannabidiol, has been the reigning trend of recent years and shows no signs of stopping. Far from ideal (but this is certainly the case), patients are advised to exercise caution and talk to their doctor before making any decision about combining CBD or THC and SSRIs. Limited research has shown that CBD can help alleviate symptoms of anxiety and sleep problems, as well as reduce levels of inflammation in the body, although this research (and the doses needed for these effects) are nowhere near conclusive.
And while CBD is touted as an all-natural supplement and there's some evidence that it may be good for your health, it's possible that coffee with milk with CBD will continue to affect the effectiveness of different medications, including antidepressants. In other words, taking CBD supplements while taking these psychiatric medications could hypothetically interfere with how these medications are metabolized.