How Does CBD Affect Brain Chemicals?

CBD has the potential to affect brain function by displacing glutamate and GABA+, two neurotransmitters that play a role in excitation and inhibition. CBD also increases tryptophan levels, which is a key compound in the serotonin synthesis pathway, potentially leading to increased serotonin levels. In addition, CBD increases anandamide levels in the brain, which is one of the few natural cannabinoids produced in the body. Anandamide is involved in the regulation of other brain chemicals, such as dopamine and serotonin.

Contrary to popular belief, CBD does not interact with cannabinoid receptors, but instead stimulates the endocannabinoid system to produce more of its own cannabinoids and delays their breakdown. Delta-9-tetrahydrocannabinol (THC), on the other hand, binds to the CB1 and CB2 receptors, activating them and, therefore, changing a person's thinking, memory, pleasure, perception of pain and concentration. CBD also has an impact on numerous non-cannabinoid receptor systems in the brain. It interacts with several receptors that are sensitive to many drugs and neurotransmitters.

Through its interaction with dopamine receptors, it helps to raise dopamine levels and to regulate cognition, motivation and reward-seeking behaviors. In addition, researchers have linked increased serotonin 1A receptor activity to the possible influence of CBD on certain problems, such as depression, nausea caused by chemotherapy, neuropathic pain and schizophrenia. CBD also inhibits GPR55 signaling, which is related to its ability to stop cancer growth. It interacts with the same intracellular molecules that transport THC and anandamide to different parts of the cell interior.

Through this effect, it helps to increase the level of dopamine in the body. The unique neurological effects of CBD are the main reason why this supplement has taken over the world of wellness products. The list of medical conditions that CBD relieves includes anxiety, inflammation, pain, lethargy, aging, skin and bone injuries, and other health problems. In addition to that, numerous studies have shown that the topical use of CBD improves joint mobility and accelerates the healing process after injury.

Tonia Kilcullen
Tonia Kilcullen

Freelance social media practitioner. Lifelong writer. Typical social media specialist. Award-winning internet advocate. Devoted beer scholar.